Endophytic Actinomycetes: A Novel Antibiotic Source

Antibiotics are secondary metabolites produced by some microorganisms to inhibit or kill many other microorganisms including different bacteria, viruses and eukaryotic cells. Antibiotics are secondary metabolites and these have also been termed “idiolites” (Walker, 1974). Subsequent and widespread use of antibiotics for therapeutic purposes regularly in human, veterinary and agricultural purposes were favoring the survival and spread of resistant pathogens. Search for new natural antibiotics and new therapeutic agents by continuous screening of secondary microbial products produced from potential bacterial taxa which overcome drug resistance of pathogenic micro flora are the viable solution to this problem (Gebreselema et al., 2013). Such research necessitates the systematic screening of producers of antibacterial antibiotic from unexplored sources. International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 8 (2016) pp. 164-175 Journal homepage: http://www.ijcmas.com